PHYLOBOT: A WEB PORTAL FOR AUTOMATED PHYLOGENETICS, ANCESTRAL SEQUENCE RECONSTRUCTION, AND EXPLORATION OF MUTATIONAL TRAJECTORIES.

PhyloBot: A Web Portal for Automated Phylogenetics, Ancestral Sequence Reconstruction, and Exploration of Mutational Trajectories.

The method of phylogenetic ancestral sequence reconstruction is a powerful approach for studying evolutionary relationships among protein sequence, structure, and function.In particular, this approach allows investigators to (1) reconstruct and "resurrect" (that is, synthesize in vivo or in vitro) extinct proteins to study how they differ from mode

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Persistent Chronic Periprosthetic Joint Infection Treated with Three-Stage Revision Hip Arthroplasty: A Case Report

Background: Periprosthetic Joint Infection (PJI) is a dreadful complication of primary Total Hip Arthroplasty (THA).Following revision THA, up to 17% of revision THA can be complicated with PJI.Three-stage revision should only be done if simple debridement fails to treat PJI.Here we present a rare case of persistent PJI, treated with three-stage re

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A System for Surgeon Fatigue Monitoring in Robotic Surgery

Surgeon fatigue during robotic surgery is an often-overlooked factor contributing to patient harm.This study presents the design, development, and The Last Knight testing of a real-time fatigue monitoring system aimed at enhancing safety in robotic surgery using the da Vinci surgical system.The system monitors critical fatigue indicators, including

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